Labs: TSH: 8.75; free T4: 0.95, increased TPO ab.
Nodule biopsy:
Nodule biopsy:
Diagnosis: Hashimoto's thyroiditis
In certain stimulatory conditions, such as autoimmune thyroiditis, GC B cells can have clonal or restricted proliferation. Without histological assessment, FCM can be very difficult to distinguish it from CD10+ B-cell lymphomas. Careful evaluation of the light chain expression pattern and clinical correlation are important for accurate interpretation.
In certain stimulatory conditions, such as autoimmune thyroiditis, GC B cells can have clonal or restricted proliferation. Without histological assessment, FCM can be very difficult to distinguish it from CD10+ B-cell lymphomas. Careful evaluation of the light chain expression pattern and clinical correlation are important for accurate interpretation.