Flow Cytometry:
Summary of flow cytometry results:
Abnormal cells comprise approximately 80% of total leukocytes in the sample. They are positive for CD34, CD117, CD33, CD56, CD61, CD45, CD38 (partial, 38%), CD13 (dim), CD71 (minimal, 15%); negative for HLA-DR, CD14, CD235a, cMPO, cLysozyme, TdT and T or B cell markers.
Cytogenetic:
48,XX, t(8;16)(q13;q24),+21[20]
Buccal cell: no trisomy 21
Diagnosis:
Acute megakaryoblastic leukemia.
Abnormal cells comprise approximately 80% of total leukocytes in the sample. They are positive for CD34, CD117, CD33, CD56, CD61, CD45, CD38 (partial, 38%), CD13 (dim), CD71 (minimal, 15%); negative for HLA-DR, CD14, CD235a, cMPO, cLysozyme, TdT and T or B cell markers.
Cytogenetic:
48,XX, t(8;16)(q13;q24),+21[20]
Buccal cell: no trisomy 21
Diagnosis:
Acute megakaryoblastic leukemia.