Flow cytometry study of the peripheral blood showed a myeloblast population (40% of total cells) with coexpression of CD45 (dim), CD34, CD38, HLA-DR, CD4 (dim), CD13, CD11b, CD33, CD117, and no expression of CD14, CD61, CD235a, MPO, lysozyme, T-cell or B-cell markers.
Cytochemical stain: negative for MPO and butyrate esterase.
Cytogenetics: 46,X,ins(19;X)(q11;p11.23q21.1),+ins(19;X),del(5)(q31.2),der(7)t(X;7)(q21.33;q36.3)
Diagnosis: Acute Myeloid Leukemia with minimal differentiation (FAB M0).
Cytochemical stain: negative for MPO and butyrate esterase.
Cytogenetics: 46,X,ins(19;X)(q11;p11.23q21.1),+ins(19;X),del(5)(q31.2),der(7)t(X;7)(q21.33;q36.3)
Diagnosis: Acute Myeloid Leukemia with minimal differentiation (FAB M0).