Flow cytometry study:
Cytogenetic study:
FISH: deletion of the 3' P2RY8 (Xp22.33) probe, suggesting a CRLF2/P2RY8 fusion.
Microarray: ~ 316 kb loss within Xp22.3 involving P2RY8 that is predicted to result in a P2RY8/CRLF2 fusion. ~44 kb loss which includes exons 4-6 of IKZF1.
Diagnosis:
B-ALL with CRLF2 rearrangement
FISH: deletion of the 3' P2RY8 (Xp22.33) probe, suggesting a CRLF2/P2RY8 fusion.
Microarray: ~ 316 kb loss within Xp22.3 involving P2RY8 that is predicted to result in a P2RY8/CRLF2 fusion. ~44 kb loss which includes exons 4-6 of IKZF1.
Diagnosis:
B-ALL with CRLF2 rearrangement