A 8 years old male immigrant from Southeast Asia presented with chronic jaundice. The parents know that he had some blood disorder but don't know the name. CBC: WBC 11.71k/ul, RBC 4.26m/ul, Hg 9g/dL, MCV 65.5 fL, MCH 21.1 pg, RDW-CV 26.4%, plt 347k/ul. PB smear show the following findings.
HPLC: Hb capillary electrophoresis:
Father (40yo, CBC: WBC6.08, RBC 6.9, Hg 10.7, MCV 50.7, MCH 16, RDW-CV 30.4, Plt 230):
Mother (40 yo, CBC: WBC10.01, RBC 5.81, Hg 11.1, MCV 62, MCH 19.1, RDW-CV 17.2, plt 379):