A 15 yo male with no significant past medical history presented with fatigue, petechiae and easy bruising. He also had weight loss and hepatosplenomegaly but no lymphadenopathy. CBC and PB smear review showed anemia (Hb 8.7g/dL), thrombocytopenia (plt 27K/ul) and around 10% blast-like atypical cells as seen in the following microscopic pictures. Bone marrow (BM) aspiration was performed and show around 15% blast-like atypical cells as seen in the following microscopic pictures.
PB (CELLAVISION):
BM smear:
BM biopsy: